![]() The paper referred to six orally-dosed does. Having received the results, McBride prepared a paper, adding one of the assistants as co-author. To prove this, he instructed his assistants to treat pregnant rabbits with scopolamine, an anti- cholinergic agent related to a constituent of Debendox. He became convinced that Debendox, a Merrel Dow morning sickness drug, was teratogenic. It worked in co-operation with a university and a hospital. HISTORYīecause of the fame he derived from his attention to thalidomide, McBride attracted public funds for the formation of Foundation 41, a charitable institution sponsoring studies on birth defects. ![]() The present paper is based on the Inquiry report. The findings of the Inquiry into the matter (Gibbs et al., 198B) have considerable importance for the conduct of private research organizations, publication procedures of research journals, the role of assistants in research projects, collaboration between laboratories, and methods for inquiring into allegations of malpractice. It is still not clear how much of McBride's later activities were fraud and how much poor quality research. The most recent case involved Dr William McBride, a prominent Sydney obstetrician who became well known in medical research for his part in drawing attention to the teratogenic effects of thalidomide. HUMPHREY, LLB MSc PHd School of Biological Sciences, University of Sydney, Australia 2006ĪBSTRACT Scientific fraud has occasionally been reported in Australia. Humphrey: Scientific Fraud: The McBride Case 199
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